These highlights do not include things like all the knowledge necessary to use Depakote safely and successfully. See total prescribing facts for Depakote.

For youngsters: Small children youthful than 2 decades aged have a heightened risk of liver harm even though getting this drug, particularly if Additionally they take other drugs to treat seizures.

Take care of the manic stage of bipolar problem. A manic episode is often a period of time in which your temper is amazingly strong. This may include things like an elevated or an irritated temper.

Accountable gaming begins with placing a finances. Identify just how much it is possible to find the money for to spend and follow it in order to avoid unwanted losses.

There won't be any enough experiments in Ladies for determining infant hazard when making use of this medication all through breastfeeding. Weigh the probable Added benefits from the likely pitfalls in advance of getting this medication although breastfeeding.

8)]. The benefit of enhanced therapeutic result with better doses need to be weighed in opposition to the potential for a larger incidence of adverse reactions.

For those who build these symptoms, call 911 or your neighborhood emergency companies or visit the closest unexpected emergency home.

notify your health care provider and pharmacist If you're allergic to valproic acid, some other drugs, or any of your ingredients in the sort of valproic acid that has been prescribed to suit your needs. Check with your pharmacist for a listing of the ingredients.

Valproate is for that reason contraindicated for prophylaxis of migraine complications in pregnant women As well as in women of childbearing potential who will be not employing successful contraception [see Contraindications (4)].

If you have diabetes and also your physician has explained to you to test your urine for ketones, explain to the health care provider that you're using valproic acid. Valproic acid could potentially cause Wrong effects on urine exams for ketones.

Evidence indicates that folic acid supplementation prior to conception And through the very first trimester of pregnancy decreases the chance for congenital neural tube defects in the general inhabitants [see Use in Distinct Populations (eight.1)].

Divalproex sodium, valproate sodium, and valproic acid goods are absorbed by the body in other ways and can't be substituted for one another. If you must switch from one particular merchandise to a different, your medical professional may need to adjust your dose.

Having warfarin with divalproex sodium might website raise the amounts of warfarin in Your entire body. Your doctor might check your INR far more generally if you have to consider divalproex sodium together with warfarin.

When Depakote is utilised Within this patient group, it ought to be utilized with Serious caution and being a sole agent. The advantages of therapy really should be weighed against the pitfalls. The incidence of lethal hepatotoxicity decreases considerably in progressively older patient groups.